Concentration

Definition A concentration (C) indicates the content of one substance in another as a quotient. By definition, it refers to the amount of a substance present in a given volume. However, concentrations can also refer to masses. In pharmacy, concentration is often used in connection with liquid and semisolid dosage forms. For solid dosage forms … Concentration

Active Ingredient Salts

Structure and properties Many active pharmaceutical ingredients are present in the drug as organic salts. This means that the active ingredient is ionized and its charge is neutralized by a counterion (English ). For example, naproxen is present in the over-the-counter pain reliever as a sodium salt. In this form, it is referred to as … Active Ingredient Salts

Pharmaceutical Active Ingredient

Definition Active ingredients are the active components of a drug that are responsible for its pharmacological effects. Drugs may contain a single active ingredient, multiple active ingredients, or complex mixtures such as herbal extracts. In addition to the active ingredients, a drug contains various excipients that should be as pharmacologically inert as possible. The percentage … Pharmaceutical Active Ingredient

Trometamol

Products Trometamol is found as an excipient in drugs, for example, in liquid and semisolid dosage forms. It should not be confused with triethanolamine (trolamine). Structure and properties Trometamol (C4H11NO3, Mr = 121.1 g/mol) exists as a white crystalline powder or as colorless crystals and is readily soluble in water. It contains both hydroxyl groups … Trometamol

Release (Liberation)

Definition After a drug is ingested, it passes through the esophagus into the stomach and into the small intestine. There, the active ingredient must first be released from the dosage form. This is the prerequisite for it to be absorbed into the bloodstream via the cells of the mucosa. The dosage form thus exerts a … Release (Liberation)