Products The first therapeutic monoclonal antibody was approved in 1986. Muromonab-CD3 (Orthoclone OKT3) binds to the CD3 receptor on T cells and has been used in transplantation medicine. Numerous drugs containing antibodies are now available. A selection of active substances can be found at the end of this article. These are expensive drugs. For example, … Monoclonal Antibodies
Products Therapeutic proteins are usually administered in the form of injection and infusion preparations and must be stored in a refrigerator. The first recombinant protein to be approved was human insulin in 1982. Some proteins, for example, are also available in tablet, capsule, and powder form and can be stored at room temperature, such as … Therapeutic Proteins
Products Legally, a distinction can be made between legal intoxicants (e.g., alcohol, nicotine) and prohibited substances (e.g., many hallucinogens, some amphetamines, opioids). Some substances, such as the opioids or the benzodiazepines, are used as drugs and are legally available with a doctor’s prescription. However, their use as intoxicants is not intended and is therefore referred … Intoxicant
Products Enzymes are commercially available as drugs in the form of tablets, lozenges, capsules, as well as injection and infusion preparations, among others. Many products are subject to prescription, but there are also some agents which are released for the OTC market. Structure and properties Therapeutic enzymes are usually proteins, i.e. polymers of amino acids, … Therapeutic Enzymes
Products Direct oral anticoagulants (abbreviation: DOAKs) are commercially available in the form of film-coated tablets and capsules. By definition, they are oral drugs. Some representatives of the corresponding drug groups are also available as infusion preparations. Rivaroxaban (Xarelto) and dabigatran (Pradaxa) were the first active ingredients to be approved in 2008. The DOAKs were developed … DOAK
Products Direct factor Xa inhibitors are commercially available in the form of film-coated tablets and capsules. In 2008, rivaroxaban (Xarelto) was the first agent in this group to be approved in many countries and in the EU. Today, there are other drugs on the market, which are listed below. Like thrombin inhibitors, these active ingredients … Factor Xa Inhibitors
Products Analgesics are available in numerous dosage forms. These include, for example, tablets, effervescent tablets, powders, granules, suppositories, syrups, transdermal patches, and injectables. One of the oldest painkillers is opium, which is obtained from the incised, immature capsules of the opium poppy. It has been used medicinally for thousands of years. The first synthetic analgesics, … Painkiller
Products Tolperisone is commercially available in the form of film-coated tablets (Mydocalm, generic). It has been approved in many countries since 1966. Structure and properties Tolperisone (C16H23NO, Mr = 245.36 g/mol) is chiral and is present in drugs as racemate and tolperisone hydrochloride. It is a piperidine derivative and a propiophenone. Tolperisone has structural similarities … Tolperisone
Products Rofecoxib was approved in many countries in 1999 in tablet and suspension form (Vioxx). It was withdrawn from the market again in late September 2004 because of adverse effects and is no longer available. Structure and properties Rofecoxib (C17H14O4S, Mr = 314.4 g/mol) is a methyl sulfone and a furanone derivative. It has a … Rofecoxib
Products Nitrogen is commercially available as a compressed gas in pressurized cylinders and as a liquid in cryogenic containers, among other products. Structure and properties Nitrogen (N, atomic mass: 14.0 u) is a colorless and odorless gas that is present in over 78% of air. It is a chemical element with atomic number 7 and … Nitrogen
