Most common mechanism of action Most drugs bind to a macromolecular target structure called a drug target. These are usually proteins such as receptors, transporters, channels, and enzymes, or nucleic acids. For example, opioids interact with endogenous opioid receptors to relieve pain. Targets can also be exogenous structures. Penicillins inhibit bacterial enzymes responsible for building … Mechanism of Action
Products On the one hand, anabolic steroids are on the market as approved drugs, for example testosterone and other androgens. On the other hand, many agents are also produced and distributed illegally. Structure and properties Anabolic steroids structurally correspond to or are derived from androgens, the male sex hormones. The prototype of the group is … Anabolic Steroids: Synthetic Testosterone
Products Rosuvastatin is commercially available in the form of film-coated tablets (Crestor, generic, auto-generic). It was approved in many countries in 2006 (Netherlands: 2002, EU and US: 2003). The marketing authorization holder is AstraZeneca. The statin was originally developed at Shionogi in Japan. In the USA, generic versions came on the market in 2016. In … Rosuvastatin
Symptoms Postherpetic neuralgia manifests as localizable and unilateral pain in the area that was affected by shingles, increased tenderness (allodynia1) and pruritus. The pain character is described as itchy, burning, sharp, stabbing, and throbbing, among others. The discomfort occurs even though the shingles has healed and can sometimes last for months and even years. The … Postherpetic Neuralgia
Bone infection does not always show typical symptoms, which makes it difficult to recognize the disease. In an acute illness, high fever may occur in conjunction with a strong general feeling of illness. The affected section of the bone hurts a lot and is often swollen as well. If the inflammation affects not only the … Bone Infections: Symptoms and Diagnosis
The goal of treatment is to stop the infection and halt the deterioration of the bone and surrounding soft tissues. Usually, the therapy consists of a drug and a surgical part. The administration of antibiotics is intended to kill the causative agents of the inflammation, the bacteria. For this, it is important to know the … Bone Infections: Therapy and Complications
Bacteria are not only the cause of colds or gastrointestinal infections, but also cause infections in our bones. To avoid permanent damage to bones and joints, early treatment is necessary. We inform you about different types of bone infections, typical symptoms as well as diagnosis and treatment of such an infection. What is a bone … Bone Infections: When Bacteria Attack Our Skeleton
