Products Pravastatin is commercially available in tablet form (Selipran, generics). It has been approved in many countries since 1990. Structure and properties Pravastatin (C23H36O7, Mr = 424.5 g/mol) is present in drugs as pravastatin sodium, a white to yellowish-white powder or crystalline powder that is readily soluble in water. It is not a prodrug, unlike … Pravastatin
Products Rosuvastatin is commercially available in the form of film-coated tablets (Crestor, generic, auto-generic). It was approved in many countries in 2006 (Netherlands: 2002, EU and US: 2003). The marketing authorization holder is AstraZeneca. The statin was originally developed at Shionogi in Japan. In the USA, generic versions came on the market in 2016. In … Rosuvastatin
Products Fluvastatin is commercially available in the form of capsules and sustained-release generic tablets (generics). It has been approved in many countries since 1993. Sales of the original Lescol were discontinued by Novartis in 2018. Structure and properties Fluvastatin (C24H26FNO4, Mr = 411.5 g/mol) is present in drugs as fluvastatin sodium, a white or pale … Fluvastatin
Products Cerivastatin was commercially available in the form of film-coated tablets (Lipobay, Baycol). Because of rare possible adverse effects, it was withdrawn from the market in August 2001 (see below). Structure and properties Cerivastatin (C26H34FNO5, Mr = 459.6 g/mol) is a pyridine derivative and is present in drugs as cerivastatin sodium. Unlike other statins, it … Cerivastatin
Products Pitavastatin is commercially available in the form of film-coated tablets (Livazo). It was first approved in many countries in July 2012. In Japan, it has been on the market since 2003, and it is also available in other countries such as the United States and Germany. Structure and properties Pitavastatin (C25H24FNO4, Mr = 421.5 … Pitavastatin
Products Simvastatin is commercially available in the form of film-coated tablets (Zocor, generics). It is also combined fixed with ezetimibe (Inegy, generic). Simvastatin has been approved in many countries since 1990. Structure and properties Simvastatin (C25H38O5, Mr = 418.6 g/mol) exists as a white crystalline powder that is practically insoluble in water. It is a … Simvastatin: Drug Effects, Side Effects, Dosage and Uses
