Malfunctions | Endothelium

Malfunctions Various risk factors such as arterial hypertension, increased cholesterol levels and especially nicotine consumption seriously alter the function of the intact endothelium. One speaks then of an endothelial dysfunction. For example, oxidative stress can alter the nitric oxide mechanism and highly toxic metabolites are formed which can damage the endothelium. Endothelial damage is the … Malfunctions | Endothelium

Epithelial-mesenchymal Transition: Function, Role & Diseases

Epithelial-mesenchymal transition, or EMT, refers to the transformation of epithelial cells into mesenchymal cells. This transformation possesses great importance in embryonic development. However, this process also plays a key role in the development of metastases in carcinomas. What is epithelial-mesenchymal transition? Epithelial-mesenchymal transition is a conversion of already differentiated epithelial cells into undifferentiated mesenchymal stem … Epithelial-mesenchymal Transition: Function, Role & Diseases

Blood-urinary Barrier: Structure, Function & Diseases

The nephrologist understands the blood-urine barrier to be a filtration barrier consisting of renal corpuscles and Bowman’s capsule. Because of the permselectivity of the barrier, blood proteins are not filtered out by the kidneys. In inflammatory processes in the renal corpuscles, the blood-urine barrier may be disrupted. What is the blood-urine barrier? The blood-urine barrier … Blood-urinary Barrier: Structure, Function & Diseases

Detoxification

Definition Detoxification is the process of removing or removing and metabolising substances that are harmful to the body. A detox can either be initiated or carried out by the body itself, e.g. when the amount of harmful substances exceeds a certain level, or it can be induced from the outside by the administration of drugs … Detoxification

Arteriogenesis: Function, Role & Diseases

Arteriogenesis refers to the growth of collateral arteries after stenosis and is distinct from angiogenesis. Factors such as shear forces, vascular dilatation, and monocyte accumulation play a role in the process. In the future, patients will likely be able to undergo “natural” bypass by inducing arteriogenesis. What is arteriogenesis? Arteriogenesis refers to the growth of … Arteriogenesis: Function, Role & Diseases