Benzodiazepines Effects and Side Effects

Products Benzodiazepines are commercially available in the form of tablets, melting tablets, capsules, drops, and injectables, among others (selection). Chlordiazepoxide (Librium), the first benzodiazepine, was synthesized in the 1950s by Leo Sternbach at Hoffmann-La Roche and was launched in 1960. The second active ingredient, the well-known diazepam (Valium), was launched in 1962. Numerous other drugs … Benzodiazepines Effects and Side Effects

Flumazenil: Effects, Uses & Risks

Flumazenil is an imidazole derivative of the benzodiazepines and acts as an antidote (antidote) in benzodiazepine overdose. It cancels all effects of the benzodiazepines used in anesthetics or sleeping pills for sedation. Flumazenil also reverses the influences of other non-benzodiazepines that react by the same mechanism. What is flumazenil? Flumazenil cancels all the effects of … Flumazenil: Effects, Uses & Risks

Diazepam: Effects, Uses & Risks

Diazepam is a psychotropic drug belonging to the group of tranquillizers. It is primarily used to treat anxiety and epilepsy. Diazepam is a benzodiazepine that has become known by the trade name Valium. What is diazepam? Diazepam is a psychotropic drug in the tranquilizer group. It is primarily used to treat anxiety and epilepsy. As … Diazepam: Effects, Uses & Risks

Z-Drugs

Products Z-drugs – they are also called Z-substances – are usually taken in the form of film-coated tablets. In addition, other dosage forms such as sustained-release tablets and effervescent tablets are commercially available. Zolpidem (Stilnox) was the first substance from this group to be approved in many countries in 1990. In the literature, alluding to … Z-Drugs

Intravenous Injection

Definition In an intravenous injection, a small volume of a drug is administered into a vein using a needle and syringe. The active ingredients disperse into the bloodstream and reach their site of action. For repeated administration, venous access is established with a peripheral venous catheter. Larger volumes can be infused during an intravenous infusion. … Intravenous Injection

Flumazenil

Products Flumazenil is commercially available as a solution for injection (Anexate, generics). It was developed at Roche and has been approved in many countries since 1986. Structure and properties Flumazenil (C15H14FN3O3, Mr = 303.3 g/mol) exists as a white crystalline powder that is very sparingly soluble in water. It has a comparable structure to other … Flumazenil

Benzodiazepines

Benzodiazepine is a drug that acts in the CNS and has an anxiolytic and sedative effect. Effect Stimulating and inhibiting nerve fibres and nerve cells coexist in the CNS. The associated messenger substances (transmitters) also have an excitatory or inhibitory effect. The main transmitter of the inhibiting nerve fibres is GABA (gamma-aminobutyric acid). This substance … Benzodiazepines