ganglia

What is the life expectancy with Hirschsprung’s disease? Whether or not life expectancy is limited with Hirschsprung’s disease depends on the accompanying malformations that also affect a patient. In 70% of cases, the affected children are completely healthy except for Hirschsprung’s disease. Life expectancy is not restricted and is the same as for other children. … What is the life expectancy with Hirschsprung’s disease? | Hirschsprung’s disease

Definition Hirschsprung’s disease is a rare congenital disease. It occurs with a frequency of about 1 : 3. 000 – 5. 000 affected newborns. The disease manifests itself in the gastrointestinal tract. In one part of the intestine, nerve cells and nerve cell bundles (ganglia) are missing. This is known as aganglionosis. In addition to … Hirschsprung’s disease

Symptoms The symptoms of Hirschsprung’s disease are already apparent in the newborn. The child is conspicuous by a strongly inflated abdomen. On the other hand, the first thin stool (technically called meconium) should be excreted within the first 24 to 48 hours. In newborns with Hirschsprung’s disease, the first stool is given late or usually … Symptoms | Hirschsprung’s disease

Therapy of Hirschsprung’s disease Treatment of Hirschsprung’s disease cannot be conservative, but must be carried out surgically. In the beginning, an artificial bowel outlet is created surgically (anus praeter), so that the bowel can be emptied. The artificial bowel outlet is created in front of the site affected by the disease. This allows the disease … Therapy of Hirschsprung’s disease | Hirschsprung’s disease

Complications Since the stool often fails to pass in newborns with Hirschsprung’s disease, an artificial stool evacuation must be performed. If this is not carried out in time, a complication known as necrotizing enterocolitis can occur, which is an acute, life-threatening disease of the gastrointestinal tract. If the accumulated stool is excessively colonized with bacteria, … Complications | Hirschsprung’s disease

Inheritance in Hirschsprung’s disease Hirschsprung’s disease is an inherited disease. It is not possible to determine a specific gene as the trigger of the disease. Depending on which gene is affected, the disease is inherited autosomal-dominantly or autosomal-recessively. Autosomal-dominant means that if the newborn child inherits a diseased gene from one parent, it is automatically … Inheritance in Hirschsprung’s disease | Hirschsprung’s disease