What are petechiae? Petechiae are small punctiform bleedings that can occur in all organs. Typically, petechiae become noticeable when they are in the skin. Petechiae cannot be pushed away, unlike other punctiform changes in the skin. If you press the petechiae with a glass spatula, they do not disappear, as they are bleedings and not … Causes of petechiae
Definition A decrease in the number of platelets due to the administration of heparin is called heparin-induced thrombocytopenia (HIT). A distinction is made between two forms, the non-immunological form (HIT type I) and the antibody induced form (HIT type II). Introduction The word thrombocytopenia refers to a deficiency of thrombocytes, i.e. blood platelets. The word … Heparin-induced thrombocytopenia (HIT)
Causes Heparin-induced thrombocytopenia are either formed as a non-immunological, harmless early form (type I) or are based on the formation of antibodies against platelet factor 4/heparin complex (type II). These cause the blood to clump together and the platelets are, so to speak, “caught away” or “trapped”, they can no longer perform their natural function.Unfractionated … Causes | Heparin-induced thrombocytopenia (HIT)
Therapy The most important step in therapy is the immediate discontinuation of heparin if type II HIT is suspected. Also all other drugs containing heparin must not be used any further to prevent possible complications. These include ointments or catheter irrigations containing heparin. The anticoagulant therapy must be changed to non-heparin-based substances in order to … Therapy | Heparin-induced thrombocytopenia (HIT)
Introduction Mono-Embolex® is a so-called anticoagulant, i.e. a drug that inhibits blood coagulation (anticoagulant) and is thus used primarily for the prophylaxis and therapy of venous thrombosis and pulmonary embolism. The active ingredient of the preparation Mono-Embolex® is certoparin sodium. The active ingredient Certoparin belongs to the class of low molecular weight (=fractionated) heparins. These … Mono-Embolex
Fields of application Low molecular weight heparins such as the active ingredient certoparin in Mono-Embolex® are suitable for thrombosis prophylaxis and thrombosis therapy. Thrombosis is a disease that occurs in the blood vessels. A blood clot is formed via the coagulation cascade, which closes the blood vessel. Often thromboses are localized in the veins and … Fields of application | Mono-Embolex
Therapy monitoring In contrast to a standard heparin, the fluctuations of the drug level in the body are significantly lower with low-molecular-weight heparin. For this reason, therapy monitoring is usually not absolutely necessary. Exceptions are patients who have an increased risk of bleeding and/or patients who suffer from renal insufficiency. In such cases, the determination … Therapy monitoring | Mono-Embolex
Pregnancy and lactation There is a lot of experience regarding the use of low molecular weight heparins in pregnancy. In the first 12 weeks of pregnancy, no harmful effect on the embryo could be observed when using Mono-Embolex®. This finding is based on approximately 2,800 observed pregnancies under Certoparin therapy. Mono-Embolex® does not appear to … Pregnancy and lactation | Mono-Embolex
Heparin-induced thrombocytopenia is a condition that can occur after the administration of heparin. In this condition, the number of platelets in the blood drops below 50 percent of normal. What is heparin-induced thrombocytopenia? Heparin-induced thrombocytopenia (HIT) is a complication of treatment with heparin. Heparin is a standard medical drug used for anticoagulation (inhibition of blood … Heparin-induced Thrombocytopenia: Causes, Symptoms & Treatment
