Products Dihydrotachysterol is commercially available as an oily solution (A.T. 10). It has been approved in many countries since 1952. Structure and properties Dihydrotachysterol (C28H46O, Mr = 398.7 g/mol) is a lipophilic analog of vitamin D. Effects Dihydrotachysterol (ATC A11CC02) has multiple properties in calcium metabolism. The compound is already active and does not need … Dihydrotachysterol
Products Calcitriol is commercially available in the form of capsules (e.g., Rocaltrol) and as an ointment for psoriasis (Silkis). The active ingredient has been approved in many countries since 1978. The oral solution has been off the market since 2012. The active ingredient content could not be ensured until the end of the shelf life. … Calcitriol Effects and Side Effects
Structure and properties Polypeptide composed of 84 amino acids Synthesis and release Formation in the parathyroid glands Effects Bone resorption by activation of osteoclasts: increase in blood calcium levels Effect on kidney: Decrease in phosphate reabsorption: decrease in blood phosphate level. Decrease in calcium excretion: increase the level of calcium in the blood. Stimulation of … Parathyroid Hormone
Synonym Medical: Hypoparathyroidism Definition Hypothyroidism (hypoparathyroidism) is a disease of the parathyroid gland that leads to a parathyroid hormone deficiency. This lack of parathyroid hormones leads to a lack of calcium throughout the body, which can cause neurological symptoms. Ethiology The most common cause of hypothyroidism is a surgically induced removal of the parathyroid glands … Parathyroid hypothyroidism
Complications Complications of parathyroid hypothyroidism occur mainly when the parathoromone deficiency is not detected in time. In children this can lead to dental anomalies, developmental disorders and dwarfism. In adults, late damage from parathyroid hormone deficiency can occur if it is not detected early and treated with medication. These include heart problems, cataracts, osteoporosis and … Complications | Parathyroid hypothyroidism
Prophylaxis In principle, the parathyroid glands should not be damaged or removed in any thyroid surgery. If this is not possible, there is the possibility of autotransplantation. In this case the patient’s own parathyroid glands can be planted into muscle tissue. These grow into these areas and continue to produce parathyroid hormone. This option is … Prophylaxis | Parathyroid hypothyroidism
Pseudohypoparathyroidism shows the same symptoms as normal hypoparathyroidism without a deficiency of parathyroid hormone. Blood levels of calcium are found to be too low and phosphate too high. Despite a normal or even elevated concentration, parathyroid hormone is unable to exert its effect. What is pseudohypoparathyroidism? Pseudohypoparathyroidism, also known as Martin-Albright syndrome, is characterized by … Pseudohypoparathyroidism: Causes, Symptoms & Treatment
Microdeletion syndrome 22q11 refers to chromosomal abnormalities that affect the long arm of chromosome 22 in gene locus 22q11 and manifest as malformation syndromes. In most cases, affected individuals suffer from a heart defect, fascial malformations and thymic hypoplasia. Treatment is symptomatic and focuses mainly on the correction of malformed organs. What is 22q11 microdeletion … Microdeletion Syndrome 22Q11: Causes, Symptoms & Treatment
