Products Bisphosphonates are commercially available in the form of film-coated tablets and as injection and infusion preparations. They are also combined fixed with vitamin D3. Their effects on bone were described in the 1960s. Etidronate was the first active ingredient to be approved (out of trade). Structure and properties Bisphosphonates contain a central carbon atom … Bisphosphonates Effects and Side Effects
Definition and properties When we take a tablet or capsule, it contains a defined amount of an active pharmaceutical ingredient. Usually, the full dose does not enter the bloodstream. Some active ingredients are not fully released from the dosage form (liberation), others are only partially absorbed from the intestine (absorption), and some are metabolized in … Bioavailability
Products Ibandronate is commercially available as film-coated tablets (monthly tablets containing 150 mg of ibandronic acid) and as a solution for injection (Bonviva, generics). The daily tablets containing 2.5 mg of active ingredient are no longer available. This article refers to oral and monthly osteoporosis therapy. Ibandronate is also used in tumor treatment. Ibandronate was … Ibandronate
Symptoms In osteoporosis, bones become weak, porous, and brittle and undergo structural changes. Even minor stresses can lead to a fracture, especially of the vertebrae, femoral neck, and wrists. Fractures pose a risk to the elderly and can lead to pain, hospitalization, surgery and disability. In the worst cases, they are even life-threatening. Other possible … Osteoporosis Causes and Treatment
Definition Bonviva® is a drug from the bisphosphonate drug group. Bisphosphonates are also known as diphosphonates. It is a chemical compound with two phosphate groups. Bonviva® contains the active ingredient ibandronic acid (ibandronate). Mode of action The active ingredient ibandronic acid belongs to the group of bisphosphonates, which have a chemical structure in which two … Bonviva®
Interactions with other medicines A complication was observed when taking the drug if polyvalent cations were added at the same time. This leads to an interaction in which stable and poorly absorbed complexes are formed. In addition, the absorption is further deteriorated. Bonviva® should also be taken in an empty state, i.e. about half an … Interactions with other medicines | Bonviva®
