Products Prostaglandin analogues are commercially available in the form of eye drops in vials or as monodoses without preservatives. Latanoprost (Xalatan) was the first agent from this group to be approved in 1996. Prostaglandin analogues are also combined with the beta-blocker timolol fix. Structure and properties Prostaglandin analogs are derivatives of prostaglandin F2α. Except for … Prostaglandin Analogs
Products Latanoprost is commercially available as eye drops in dropper bottles and as monodoses (Xalatan, generic, auto-generic, 50 µg/ml). It is also available as a fixed combination with timolol (Xalacom, generic, auto-generic). Latanoprost was developed in the 1980s as part of a collaboration between Columbia University in New York and Pharmacia in Uppsala, Sweden (Stjernschantz, … Latanoprost
Products Latanoprostenebunod was approved in the United States in 2017 in the form of eye drops (Vyzulta). Structure and properties Latanoprostenebunod is a prodrug that is metabolized in the eye to latanoprost acid and butanediol mononitrate. Butanediol mononitrate is further biotransformed to 1,4-butanediol and nitric oxide (NO). Latanoprost acid is also formed from latanoprost, which … Latanoprostenbunod