Products Opicapone was approved in the EU in 2016 and in many countries in 2018 in hard capsule form (Ongentys). Structure and properties Opicapone (C15H10Cl2N4O6, Mr = 413.2 g/mol) is an oxadiazole derivative with a pyridine–oxide at position 3. The compound was designed with the goal of developing an effective and safer COMT inhibitor. This … Opicapon
Products Lumiracoxib (Prexige, Joicela, film-coated tablets) is no longer on the market or has not been approved in many countries because of its liver-toxic properties. The drug was not registered in many countries. Structure and properties Lumiracoxib (C15H13ClFNO2, Mr = 293.7 g/mol) is an analog of diclofenac (Voltaren) and belongs to the phenylacetic acid derivatives. … Lumiracoxib