Tezacaftor

Products Tezacaftor was approved in the US and EU in 2018 and in many countries in 2019 in fixed combination with previously registered ivacaftor in film-coated tablet form (Symdeko). In 2020, a fixed combination with tezacaftor, elexacaftor, and ivacaftor was approved (Trikafta). Structure and properties Tezacaftor (C26H27F3N2O6, Mr = 520.5 g/mol) exists as a white … Tezacaftor