Oxazolidinones

Effects Oxazolidinones have antibacterial activity against aerobic Gram-positive bacteria and anaerobic microorganisms. They bind to bacterial ribosomes and prevent the formation of a functional 70S initiation complex, and thus an essential step during the translation process. Indications For the treatment of bacterial infectious diseases. Active ingredients Linezolid (Zyvoxide) Tedizolid (Sivextro)

Tedizolid

Products Tedizolid is commercially available as an infusion preparation and in tablet form (Sivextro). It was approved in the United States in 2014 and in many countries and the EU in 2015. Structure and properties Tedizolid (C17H15FN6O3, Mr = 370.3 g/mol) is present in the drug in the form of the prodrug tedizolid phosphate, a … Tedizolid