Products Tafamidis was approved in the EU in 2011, in the US in 2019, and in many countries in 2020 in soft capsule form (Vyndaqel). Structure and properties Tafamidis (C14H7Cl2NO3, Mr = 308.1 g/mol) is present in the drug either as tafamidis meglumine or as tafamidis. Effects Tafamidis (ATC N07XX08) is a selective stabilizer of … Tafamidis
Definition The duodenal ulcer (Ulcus duodeni) is an inflammatory wound of the intestinal mucosa in the area of the duodenum. The duodenum is the first section of the small intestine following the stomach. The ulcer, i.e. the wound, extends beyond the muscle layer of the mucous membrane of the small intestine (lamina muscularis mucosae). Dangerous … Duodenal ulcer
Causes In the development of duodenal ulcers, the balance between protective and aggressive factors in the intestinal mucosa plays a role. In a healthy body, the aggressive stomach acid that flows from the stomach into the duodenum is neutralized by a protective layer of mucus on the intestinal mucosa. If this balance is destroyed, i.e. … Causes | Duodenal ulcer
Can a duodenal ulcer become malignant? A malignant (malignant) degeneration rarely occurs in duodenal ulcers. Malignant degeneration occurs in about 1-2% of patients with peptic ulcer, and in duodenal ulcer degeneration is much rarer. In chronic cases, degeneration is generally more probable, which is why an endoscopic examination should be performed at least every two … Can a duodenal ulcer become malignant? | Duodenal ulcer
Diagnosis The diagnosis of duodenal ulcer consists of several steps. First of all, a detailed patient interview (anamnesis) is made with subsequent examination of the patient. A rectal examination by palpation is seldom carried out during which non-visible – so-called occult – blood in the stool can be detected. A reliable diagnosis is made by … Diagnosis | Duodenal ulcer
Prophylaxis The best prevention against intestinal diseases in general is a healthy, balanced diet and sufficient fluid intake of at least 1.5 liters per day. In terms of nutrition, fiber, fruit and vegetables should be on the daily menu. Enteritis can often be prevented by adequate hygiene. Many of the pathogens cannot survive outside the … Prophylaxis | Inflammation of the small intestine
Introduction The small intestine with its 5-6 meters length connects the stomach with the large intestine. The small intestine is divided into 3 parts. At the beginning, directly following the stomach gate, there is the approximately 30 cm long duodenum (=doudenum), whose main task is the neutralization of the gastric hydrochloric acid as well as … Inflammation of the small intestine
Diagnosis The diagnosis of a stomach flu is usually made quite simply on the basis of the symptoms. Which pathogen causes the inflammation is usually irrelevant, since in most cases they all heal within a few days. Only if the diarrhea and the symptoms persist, the specific pathogen is filtered out of a stool sample … Diagnosis | Inflammation of the small intestine
Superior mesenteric artery syndrome is a compression syndrome that results in upper abdominal pain, difficulty eating, and nausea and even vomiting. Patients often suffer from malnutrition, which is often mistaken by those around them for the effects of an eating disorder. Treatment is primarily invasive and consists of decompression to restore normal food intake. What … Superior Mesenteric Artery Syndrome: Causes, Symptoms & Treatment
Duration of upper abdominal pain The duration of the pain and the treatment depends strongly on the underlying diseases. Probably the most common complaints in the upper abdomen occur every day and are related to the stomach and digestion. These problems usually resolve themselves within a few hours. If infections and inflammations requiring treatment are … Duration of upper abdominal pain | Upper abdominal pain
General information The upper abdomen connects directly to the two costal arches towards the bottom and merges blurred into the middle abdomen. This division of the abdomen is important with regard to the organs located in that area, which can cause corresponding pain. Pain that starts at the costal arches and goes down to the … Upper abdominal pain
Temporal occurrence of upper abdominal pain The mere fact that one notices nocturnal upper abdominal pain speaks a little for the intensity of the pain. This is why such upper abdominal pain always requires clarification, especially when the abdomen is hardened at the same time and those affected show defensive tension when touched. Children with … Temporal occurrence of upper abdominal pain | Upper abdominal pain