Antiarrhythmics

Indications For the treatment of cardiac arrhythmias. Active ingredients Class I (sodium channel blockers): class IA: Ajmaline (off-label). Quinidine (out of trade) Procainamide (out of commerce) Class IB: Lidocaine Phenytoin (not approved for this indication in many countries). Tocainide (not commercially available in many countries). Mexiletine (not on sale in many countries). Class IC: Encainid … Antiarrhythmics

Vernakalant

Products Vernakalant is commercially available as a concentrate for the preparation of an infusion solution (Brinavess). It is approved in many countries the year 2011. Structure Vernakalant (C20H32ClNO4, Mr = 385.9 g/mol) is an enantiomerically pure pyrrolidinol compound. It is present in drugs as vernakalanth hydrochloride. Effects Vernakalant (ATC C01BG11) has antiarrhythmic properties at the … Vernakalant