Products Propafenone is commercially available in the form of film-coated tablets (Rytmonorm). It has been approved in many countries since 1983. Structure and properties Propafenone (C21H27NO3, Mr = 341.4 g/mol) is present in the drug as propafenone hydrochloride, colorless crystals or a white crystalline powder that is sparingly soluble in water. The substance has a … Propafenone
Products Encainid is no longer registered in many countries. Enkaid capsules are also out of commerce in the United States. Structure and properties Encainide (C22H28N2O2, Mr = 352.5 g/mol) is present in drugs as encainide hydrochloride, a white substance which is readily soluble in water. Effects Encainide (ATC C01BC08) has antiarrhythmic properties. Indications For the … Encainid
Products Sotalol is commercially available in tablet form (generic). It has been approved in many countries since 1980. The original Sotalex is out of commerce. Structure and properties Sotalol (C12H20N2O3S, Mr = 272.4 g/mol) is present in drugs as sotalol hydrochloride, a racemate and white powder that is readily soluble in water. Sotalol is a … Sotalol
Products Quinidine is no longer registered as a drug in many countries. Kinidine Duriles is out of commerce. Structure and properties Quinidine (C20H24N2O2, Mr = 324.4 g/mol) is present in drugs as quinidine sulfate, a white crystalline powder or fine, silky, colorless needles, which are sparingly soluble in water. Effects Quinidine (ATC C01BA01) has antiarrhythmic … Quinidine
Products Dronedarone is commercially available in the form of film-coated tablets (Multaq). It was approved in 2009, first in the United States, then in Canada, in many countries, and in November throughout the European Union. Structure and properties Dronedarone (C31H44N2O5S, Mr = 556.76 g/mol) is a benzofuran derivative and an analog of the antiarrhythmic drug … Dronedarone
Products Ajmaline (gilurytmal) is not on the market in many countries. Structure Ajmaline (C20H26N2O2, Mr = 326.4 g/mol) Effects Ajmaline (ATC C01BA05) has antiarrhythmic properties. Indications For the treatment of cardiac arrhythmias.
Products Adenosine is commercially available as a solution for injection (Krenosin). It has been approved in many countries since 1992. Structure and properties Adenosine (C10H13N5O4, Mr = 267.2 g/mol) exists as a white crystalline powder that is sparingly soluble in water at room temperature and more soluble in hot water. Effects Adenosine (ATC C01EB10) is … Adenosine
Products Amiodarone is commercially available in tablet form and as a solution for injection (Cordarone, generics). It has been approved in many countries since 1968. Structure and properties Amiodarone (C25H29I2NO3, Mr = 645.3 g/mol) is an iodinated benzofuran derivative derived from khellin. It is present in drugs as amiodarone hydrochloride, a white, fine, crystalline powder … Amiodarone (Nexterone) for Arrhythmia
Products Medicines containing procainamide are no longer on the market in many countries. In some other countries, it is available as a solution for injection. Structure and properties Procainamide (C13H21N3O, Mr = 235.3 g/mol) is a derivative of the local anesthetic procaine. Procaine is an ester; procainamide is an amide. Procainamide is present in drugs … Procainamide
Products Ibutilide was commercially available as an infusion solution (Corvert). It has been approved in many countries since 1997. It was discontinued in 2018. Structure Ibutilide (C20H36N2O3S, Mr = 384.6 g/mol) is present as a racemate and ibutilide fumarate, a white powder soluble in water. Effects Ibutilide (ATC C01BD05) has antiarrhythmic properties. The effects are … Ibutilide
Products Mexiletine is commercially available in the form of capsules. No drugs containing the active ingredient are currently registered in many countries. Structure and properties Mexiletine (C11H17NO, Mr = 179.3 g/mol) is present in drugs as mexiletine hydrochloride, a white, crystalline powder with a slightly bitter taste that is readily soluble in water. It is … Mexiletin
Products Vernakalant is commercially available as a concentrate for the preparation of an infusion solution (Brinavess). It is approved in many countries the year 2011. Structure Vernakalant (C20H32ClNO4, Mr = 385.9 g/mol) is an enantiomerically pure pyrrolidinol compound. It is present in drugs as vernakalanth hydrochloride. Effects Vernakalant (ATC C01BG11) has antiarrhythmic properties at the … Vernakalant
