Products Cisplatin is available as an infusion concentrate. Several generic products are available in many countries. Platinol is out of commerce. Structure and properties Cisplatin (PtCl2(NH3)2, Mr = 300.1 g/mol) or -diammine dichloroplatinum(II) exists as a yellow powder or as orange-yellow crystals and is sparingly soluble in water. It is an inorganic heavy metal complex … Cisplatin
Products Alkaloids and their derivatives are contained as active ingredients in numerous medicines. They have been used medicinally for thousands of years, such as opium with morphine or coca leaves with cocaine. In 1805, a pure alkaloid was extracted for the first time by the German pharmacist Friedrich Sertürner with morphine. Structure and properties Alkaloids … Alkaloids
Products Vinblastine is commercially available as an injectable (Velbe). It has been approved in many countries since 1961. Structure and properties Vinblastine is present in drugs as vinblastine sulfate (C46H60N4O13S, Mr = 909 g/mol) is present, a white to slightly yellowish, very hygroscopic powder that is readily soluble in water. It is a vinca alkaloid … Vinblastine
Symptoms Lung cancer may initially be asymptomatic. It is often discovered only when it is no longer curable. Possible typical symptoms include a chronic cough, coughing up blood, difficulty breathing, recurrent colds, chest pain, and weakness, fatigue, lack of appetite, and weight loss. If spread further, additional symptoms include hoarseness, noises when breathing, and difficulty … Lung Cancer Causes and Treatment
P-glycoprotein P-glycoprotein (P-gp, MDR1) is a primary active efflux transporter with a molecular weight of 170 kDa, belonging to the ABC superfamily and consisting of 1280 amino acids. P-gp is the product of the -gene (formerly: ). P is for , ABC is for . Occurrence P-glycoprotein is found on various tissues of the human … P-Glycoprotein
The drug vinblastine belongs to the group of chemotherapeutic agents. It is used to treat cancer. What is vinblastine? Vinblastine is also known in medicine as vinblastine sulfate or vincaleukoblastine. The chemotherapeutic agent is considered the best-known representative of the vinca alkaloids. Vinblastine represents an alkaloid of the pink catharanth. This plant is also called … Vinblastine: Effects, Uses & Risks