Introduction Lymph gland cancer describes a degeneration of cells in lymph nodes and lymphatic tissues, such as the lymphatic tissue in the intestine, spleen or brain. There are two types of lymph gland cancer: Hodgkin’s lymphoma and non-Hodgkin’s lymphomas, although the latter are much more common (about 85% of lymph gland cancers). They all manifest … Lymph gland cancer
Symptoms of lymph gland cancer Typical for lymph gland cancer are painlessly enlarged lymph nodes that cannot be linked to an infection. They can occur in different parts of the body and usually persist for a long period of time. They are often palpable on the neck, in the armpits or in the groin. Enlarged … Symptoms of lymph gland cancer | Lymph gland cancer
Causes Concrete causes for the development of lymph gland cancer are still unknown. However, it is assumed that several factors must coincide for malignant lymphoma to develop. In Hodgkin’s disease, abnormal B-cells are formed, whose task is normally the production of antibodies. These cells belong to the group of lymphocytes and play an important role … Causes | Lymph gland cancer
Therapy In Hodgkin’s lymphoma, the therapy approach is always a cure of the disease and an elimination of the tumor cells within three months. The therapy is always based on chemotherapy and radiation. In stages I and II, two cycles of chemotherapy with four substances (ABVD scheme) are performed simultaneously with local radiation of the … Therapy | Lymph gland cancer
Prognosis The prognosis for Hodgkin lymphoma is very good. After five years, 80 to 90% of all patients are still living without the disease having returned. In children, this rate is even higher with over 90% of disease-free surviving patients after five years. Two thirds of recurrences occur in the first year after completed therapy, … Prognosis | Lymph gland cancer
Stadiums The stages of lymph gland cancer are classified according to Ann-Arbor in 4 stages. If only lymph nodes are affected, stages I-III are given the designation N. If other regions outside the lymph nodes are affected, E (for Extranodal) is added to the stage. In addition, the presence of B symptoms can be indicated … Stadiums | Lymph gland cancer
Frequency The British physician and pathologist Thomas Hodgkin (*1798) examined different diseases of the lymphatic system, among other things the lymph gland cancer. Hodgkin’s disease (also: lymphogranulomatosis) was first described by him in 1832 and therefore named after him. The grouping of all other malignant lymphomas into the group of non-Hodgkin lymphomas also dates back … Frequency | Lymph gland cancer
Therapy for lymph node cancer The goal, both in Hodgkin’s disease treatment and in the treatment of non-Hodgkin’s lymphomas, is to cure or contain the disease in all four stages described above. In general, chemotherapy and radiotherapy are available as forms of therapy, whereby radiotherapy is usually administered after chemotherapy. In stage 1 and 2 … Therapy for lymph node cancer | Lymph node cancer
Lymph node cancer – better known as lymph node cancer or lymphoma – is a malignant tumor disease in which lymphatic cells degenerate: some of the white blood cells (lymphocytes), which are normally involved in the immune system, have changed to such an extent that they lose their original function and multiply unchecked. At the … Lymph node cancer
Causes of lymph node cancer Hodgkin’s lymphoma is a degeneration of the B cells of the lymphocytes, whereby the underlying cause is unknown in most cases. A connection with an existing infection with the Epstein-Barr virus (EBV) is suspected. An existing immunodeficiency is a possible risk factor (e.g. in immunosuppressive therapy or HIV infection). More … Causes of lymph node cancer | Lymph node cancer
Synonyms in a broader sense Leukemia, white blood cancer, Philadelphia chromosome Definition CML (chronic myeloid lekemia) shows a chronic, i.e. rather slowly progressing course of the disease. This leads to the degeneration of a stem cell, which is a precursor of granulocytes in particular, i.e. cells that are important for the defence against mainly bacteria. … Chronic myeloid leukaemia (CML)
Chronic phase Most often, chronic myeloid leukaemia is discovered during the chronic phase. It corresponds to the initial stage of the disease and can last up to ten years. It often proceeds without symptoms, so that the initial diagnosis is often made rather coincidentally, e.g. in the context of a routine blood test by the … Chronic phase | Chronic myeloid leukaemia (CML)