Zolpidem: Effects, Uses, Side Effects

How zolpidem works Zolpidem is an active ingredient from the group of so-called “Z-drugs” (see initial letter). Drugs from this group have a sleep-promoting and calming (sedative) effect. The nerve cells are in contact with each other via certain interfaces, the synapses. Here they communicate with each other via activating or inhibiting messenger substances: If … Zolpidem: Effects, Uses, Side Effects

Zolpidem

Products Zolpidem is commercially available as film-coated tablets, sustained-release tablets, and effervescent tablets (Stilnox, Stilnox CR, generics, USA: Ambien). It has been approved in many countries since 1990. Structure and properties Zolpidem (C19H21N3O, Mr = 307.39 g/mol) is an imidazopyridine that is structurally distinct from the benzodiazepines. It is present in drugs as zolpidem tartrate, … Zolpidem

Night Work

Background According to the Labor Law, shift work refers to employees working staggered and alternately at the same workplace: “Shift work occurs when two or more groups of employees are assigned to work staggered and alternately at the same workplace according to a specific schedule.” This definition also refers to work during the day. From … Night Work

Narcotics Effects and Side Effects

Products The narcotics are a group of centrally acting drugs and substances, which are strongly regulated and controlled by the state respectively by the drug and health authorities. This is primarily to prevent abuse and to protect the population from the undesirable effects and addiction. Certain narcotics – for example, many potent hallucinogens – are … Narcotics Effects and Side Effects

Anxiolytics

Products Anxiolytics are commercially available in the form of tablets, capsules, and injectable preparations, among others. Structure and properties Anxiolytics are a structurally heterogeneous group. However, the representatives can be divided into different classes. These include, for example, the benzodiazepines or the tricyclic antidepressants. Effects Anxiolytics have antianxiety (anxiolytic) properties. They usually have additional effects, … Anxiolytics

Orexin Receptor Antagonists

Products Orexin receptor antagonists are commercially available in tablet form. The first agent in this group to be approved in the United States was suvorexant (Belsomra) in 2014. Lemborexant (Dayvigo) followed in 2019. Structure and properties Orexin receptor antagonists are characterized by a central ring structure to which heterocycles are attached on both sides. Effects … Orexin Receptor Antagonists

Restless Legs Syndrome Causes and Treatment

Symptoms Restless legs syndrome manifests as an uncomfortable and difficult-to-describe feeling in the legs and a strong urge to move the legs. Less commonly, the arms are also affected. The unilateral or bilateral insensations include, for example, a burning sensation, pain, pressing, creeping and a pulling sensation. The discomfort occurs mainly at rest, for example, … Restless Legs Syndrome Causes and Treatment

Sleeping Pills: Effects, Side Effects, Dosage and Uses

Products Sleeping pills are most commonly taken in the form of tablets (“sleeping pills“). In addition, melting tablets, injectables, drops, teas and tinctures are also available, among others. The technical term hypnotics is derived from Hypnos, the Greek god of sleep. Structure and properties Within the sleeping pills, groups can be identified which have a … Sleeping Pills: Effects, Side Effects, Dosage and Uses

Z-Drugs

Products Z-drugs – they are also called Z-substances – are usually taken in the form of film-coated tablets. In addition, other dosage forms such as sustained-release tablets and effervescent tablets are commercially available. Zolpidem (Stilnox) was the first substance from this group to be approved in many countries in 1990. In the literature, alluding to … Z-Drugs

Fibromyalgia Causes and Treatment

Symptoms Fibromyalgia is a chronic, noninflammatory disorder that manifests as pain throughout the body and is characterized by numerous other complaints. It is much more common in women than in men and usually first appears in middle age. Chronic, bilateral, diffuse pain. Muscle pain, pain in the limbs, back pain, joint pain, neck pain, headaches, … Fibromyalgia Causes and Treatment

Psychotropic Drugs: Types, Effects, Indications, Dosage

Products Psychotropic drugs are commercially available, for example, in the form of tablets, melting tablets, dragées, capsules, drops, solutions and as injectables. The first psychotropic drugs were developed in the 1950s. Structure and properties Psychotropic drugs vary chemically, but groups with a common structure can be identified, for example, the benzodiazepines, the phenothiazines, and the … Psychotropic Drugs: Types, Effects, Indications, Dosage

Medication Overuse

Definition Medication overuse involves using self-purchased or physician-prescribed medications for too long, too much, or too frequently. The duration of therapy prescribed by a healthcare professional or by the professional and patient information is exceeded, the maximum single or daily dose is too high because of a dose increase, or the dosing interval is too … Medication Overuse