The following symptoms and complaints may indicate Whipple’s disease:
- Weight loss
- Enteropathic arthritis (oligoarthritis/occurrence of joint inflammation (arthritis) in fewer than 5 joints)/spondyloarthropathy/sacroiliitis (inflammation of sacroiliac joint between sacrum and ilium); most common first symptom: 18%; may precede intestinal (“affecting the intestine”) symptoms by up to 10 years!)
- Synovialitis (synovial inflammation).
- Lymphadenopathy (lymph node enlargement).
- Abdominal pain (abdominal pain)
- Diarrhea (diarrhea)
- Fever
- Neurological symptomatology with amnesia (memory loss), dementia, gaze paralysis, epilepsy (seizures), gait disturbances, disturbed sleep-wake rhythm, polydipsia (abnormally increased water intake; more than 4 liters of fluid intake per day).
- Pleurisy (pleurisy), possibly pleural effusion (abnormal accumulation of fluid in the thoracic cavity, that is, between the inner wall of the chest and the lungs).
- Pericarditis (inflammation of the pericardium).
- Disorders in skin pigmentation, unspecified.
- Anemia (anemia)
- Uveitis – inflammation of the middle eye skin.
