Products
Aglepristone is commercially available as a solution for injection as a veterinary drug (alizine). It has been approved in many countries since 2004.
Structure and properties
Aglepristone (C29H37NO2, Mr = 431.6 g/mol) is a synthetic steroid. It has a similar structure to mifepristone (Mifegyne, RU 486).
Effects
Aglepristone (ATCvet QG03XB90) has antigestagagenic and antiglucocorticoid properties. The effects are due to the abrogation of the effects of the sex hormone progesterone, which plays a central role in the preparation for and maintenance of pregnancy.
Indications
Nidation prevention and interruption of pregnancy in bitches up to day 45 after mating.
