Alprostadil therapy is a drug treatment for erectile dysfunction (ED).Alprostadil is available for local (“topical”) and intraurethral (“into the urethra“) therapy.
Indications (areas of application)
- Diagnosis and therapy of erectile dysfunction.
- Short-term therapy for congenital heart defects (to keep the ductus arteriosus botalli open).
Only after careful risk-benefit assessment by the treating physician should the agent be used for:
- Phimosis (narrowing of the foreskin)
- Increased storage of connective tissue in the corpora cavernosa (fibrosis) due to previous permanent erections (priapism). This occur clustered in people who suffer from sickle cell anemia (med.: Drepanozytose; also sickle cell anemia, sickle cell anemia), thalassemia or leukemia (blood cancer)/plasmocytoma.
Contraindications
- Hypersensitivity to the active substance
- Severe heart disease (e.g., unstable angina, heart failure (cardiac insufficiency; > Grade I), coronary artery disease (coronary artery disease), cardiac arrhythmias, or constriction in the area of the heart valves)
- Myocardial infarction (heart attack) less than six months ago.
- Severe liver failure
- Acute or chronic lung disease (e.g., pulmonary edema or COPD).
- Sexually-transmitted diseases such as HIV- syphilis, hepatitis A-D.
- Persons with erectile tissue implants, anatomical deformities of the penis and acute or chronic inflammation of the foreskin, glans or urethra.
- Persons taking blood thinners (phenprocoumon).
- Persons with penile prostheses
Further notes
Erectile dysfunction is a euphemism for a man’s limb stiffness not being sufficient for sexual intercourse, and thus the man’s inability to penetrate his partner with his penis.
Men of all ages can be affected and the causes of erectile dysfunction are very diverse.
Erectile dysfunction can occur in:
- Atherosclerosis (arteriosclerosis, hardening of the arteries).
- Hypertension (high blood pressure)
- Diabetes mellitus
- Hormonal disorders
- Excessive consumption of alcohol, cigarettes and drugs.
- Partnership problems
- Mental upsets
The active ingredient alprostadil is a set to:
- MUSE (Medicinal Urethral System for Erection).
- SKAT (erectile tissue auto-injection therapy).
Ad 1) Alprostadil is introduced by intracavernosal injection (Caverject and Viridal). Coitus can usually be performed with adequate limb rigidity after onset of action.Success rates are up to 70%. Ad 2) Alprostadil is applied intraurethrally (into the urethra) and to the glans penis (glans) by the patient with the aid of an applicator. Dosing Instructions: Alprostadil should be used only two to three times a week and only once in 24 hours. Onset of action: 5-30 minutes; duration of action: 1-2 hours.
Alprostadil therapy can also be combined with psychological counseling and psychotherapy.
Benefits
Alprostadil therapy prevents erectile dysfunction, thereby restoring your natural vitality.
This leads to great mental and psychological relief. You can once again enjoy a satisfying sex life and have a gain in quality of life.
