Basal Cell Carcinoma: Test and Diagnosis

Laboratory parameters 1st order

  • Histology (fine tissue examination) from sample excision (tissue removal) or total excision (surgical removal of the tumor as a whole) [examination on HE(hematoxylin-eosin)-stained specimen].
  • Note: Trial biopsy required only if:
    • Suspected tumor type with high risk of recurrence (risk of disease recurrence; infiltrative, sclerodermal, micronodular, metatypical).
    • Superficial (“superficial”) basal cell carcinoma (sBZK; synonyms: trunk skin basal cell carcinoma; trunk skin BCCs) before a “blind” therapy procedure (topical therapy).
    • Pigmentation – due todifferential diagnosis of malignant melanoma; excisional biopsy should be considered here.
    • Clinical diagnosis not clear, so that differential diagnoses must be excluded.

Laboratory parameters 2nd order – depending on the results of the history, physical examination, etc. – for differential diagnostic clarification.

  • Small blood count
  • Differential blood count
  • Inflammatory parameter – CRP (C-reactive protein)