Medical history (history of illness) represents an important component in the diagnosis of Cushing’s disease.
Family history
- Is there a frequent history of metabolic disease in your family?
Social anamnesis
Current medical history/systemic medical history (somatic and psychological complaints).
- Have you noticed any changes in your appearance (full moon face (moon face), bull neck or buffalo neck, truncal obesity)?
- Do you feel easily exhausted, adynamic?
- Have you noticed any skin changes such as thin skin, acne, boils or red streaks especially on the hips/belly?
- Do you suffer from bone/muscle pain?
For women
- Have you noticed a male hair type on you?
- Do you suffer from loss of libido?
- Have you experienced any cycle disturbances?
- When was your last menstrual period?
For men
- Have you noticed that body features and/or hair type appear feminine?
- Do you suffer from impotence? Loss of libido?
Vegetative anamnesis incl. nutritional anamnesis.
- Have you gained body weight unintentionally? If so, how many kilograms in what time?
- Do you drink alcohol? If so, what drink or drinks and how many glasses per day?
Self history incl. medication history.
- Pre-existing conditions (metabolic diseases)
- Operations
- Allergies
Medication history
- Long-term use of glucocorticoids – are among the corticosteroids, a class of steroid hormones derived from the adrenal cortex. The naturally occurring glucocorticoids are derivatives (derivatives) of progesterone (corpus luteum hormone). These include cortisol and corticosterone, with a share of 95% and 5%, respectively. Furthermore, there are derived from the glucocorticoids, artificial corticoids with glucocorticoid effect.
- Long-term use of ACTH (adrenocorticotropic hormone; synonyms: corticotropin, corticotropic hormone, corticotropin, adrenocorticotropin) – a hormone synthesized in the anterior pituitary gland (front lobe of the pituitary gland) that regulates adrenocortical function and stimulates the production of hormones, especially cortisol.
