Products
Dimethicone is commercially available in many countries as a drug in the form of capsules as a fixed combination with other active ingredients (Carboticon). It is also present in lice remedies, cosmetics and technical agents and has been registered since 1964.
Structure and properties
Dimethicone (C2H6OSi)n exists as a clear, colorless liquid of varying viscosity and is practically insoluble in water. It is a surface-active polydimethylsiloxilane obtained by hydrolysis and polycondensation of dichlorodimethylsilane and chlorotrimethylsilane. The different types are distinguished by their nominal viscosity, which is expressed by the number after the name of the substance.
Effects
Dimethicone (ATC A03AX13) is chemically and biologically inert and is neither metabolized nor absorbed, but exerts its effects locally in the digestive tract. It is defoaming by altering surface tension and eliminates flatulence. In the treatment of head lice, the insects are physically killed.
Indications
Internally to treat flatulence and gas accumulation in the gastrointestinal tract and before diagnostic tests. Externally for the treatment of head lice.
Dosage
According to the SmPC. Oral dosage forms are usually given with or after meals, or before bedtime if needed.
Contraindications
- Hypersensitivity
For complete precautions, see the drug label.
Interactions
Interactions with other drugs are not known.
Adverse effects
There are no known adverse effects.
