The following are the most important diseases or complications that can be caused by duodenal ulcer:
Circulatory system (I00-I99)
- Myocardial infarction (heart attack) associated with Helicobacter pylori infection.
Mouth, esophagus (food pipe), stomach, and intestines (K00-K67; K90-K93).
- Duodenal hemorrhage (bleeding from the duodenum).
- Duodenal perforation (perforation of the duodenum, as a complication of ulcer).
- Penetration of the ulcer into adjacent organs such as the pancreas (penetration of the ulcer from the stomach into adjacent organs such as the pancreas)
Neoplasms – tumor diseases (C00-D48).
- MALT lymphoma (lymphomas of mucosa-associated lymphoid tissue, MALT); so-called extranodal (arising outside the lymph nodes) lymphomas; about 50% of all MALT lymphomas are diagnosed in the stomach (80% in the gastrointestinal tract); MALT lymphomas are highly favored in their development by chronic infections with the bacterium Helicobacter pylori (type B gastritis) or favored by inflammation (90% of MALT lymphomas of the stomach are Helicobacter pylori-positive); by an Erdikationstherapie (antibiotic therapy) disappear not only the bacteria, but as a result in 75% of cases also the gastric lymphoma.
Prognostic factors
- Helicobacter pylori strains isolated from patients with iron deficiency were significantly more aggressive in studies and caused more severe inflammation than those from patients without iron deficiency.
