Gastric Ulcer (Ulcus Ventriculi): Complications

The following are the most important diseases or complications that may be contributed to by gastric ulcer (ventriculi ulcer):

Blood, blood-forming organs – Immune system (D50-D90).

Circulatory system (I00-I99)

Mouth, esophagus (food pipe), stomach, and intestines (K00-K67; K90-K93).

  • Gastrocolic fistulas – nonphysiologic connections between the stomach and colon.
  • Gastric outlet stenosis – narrowing of the gastric outlet.
  • Gastric bleeding
  • Gastric perforation (stomach rupture); especially when taking NSAIDs (nonsteroidal anti-inflammatory drugs) and glucocorticoids (steroids)
  • Penetration of the ulcer – penetration of the ulcer from the stomach into adjacent organs such as the pancreas (pancreas).

Neoplasms – tumor diseases (C00-D48).

  • Gastric carcinoma (stomach cancer) (due totype A gastritis).
  • MALT lymphoma (lymphomas of mucosa-associated lymphoid tissue, MALT); so-called extranodal (arising outside the lymph nodes) lymphomas; about 50 % of all MALT lymphomas are diagnosed in the stomach (80 % in the gastrointestinal tract) (90 % of MALT lymphomas of the stomach are Helicobacter pylori-positive); MALT lymphomas are largely caused by chronic infections with the bacterium Helicobacter pylori (type B gastritis) or by inflammations of the gastric tract. favored by inflammation; by an Erdikationstherapie (antibiotic therapy) disappear not only the bacteria, but as a result in 75% of cases also the gastric lymphoma.

Prognostic factors

  • Helicobacter pylori strains isolated from patients with iron deficiency were significantly more aggressive in studies and caused more severe inflammation than those from patients without iron deficiency.