Effects
Glucocorticoid eye drops have anti-inflammatory, antiallergic, and immunosuppressive properties on the eye. They may increase intraocular pressure and promote infection.
Indications
Glucocorticoid eye drops are approved for the treatment of noninfectious inflammatory diseases of the anterior segments of the eye. They are also used in combination with antibiotics for infectious diseases of the eye.
Dosage
According to the drug label. Vials usually need to be shaken before use because the drugs are in suspension. See also under Administering eye drops.
Active Ingredients
- Dexamethasone eye drops
- Fluorometholone
- Prednisolone eye drops
- Rimexolone (off label)
Contraindications
- Hypersensitivity
- Eye infections (monotherapy)
- Tuberculosis
- Glaucoma
- Removal of foreign bodies
During use, numerous precautions must be observed. They can be found in the drug information leaflet.
Interactions
Other eye drops should not be placed in the eye at the same time, but should be spaced approximately 15 minutes apart. Because glucocorticoids can increase intraocular pressure, they attenuate the effect of antiglaucomatosa. Pressure may also increase with the use of mydriatics. Interactions with beta-blockers have been reported.
Adverse effects
Possible adverse effects include local irritation after administration and hypersensitivity. Frequently, and especially with prolonged use, there is an increase in intraocular pressure, infection, due to the immunosuppressive properties of the agents, and cataract.
