Therapeutic target
Regression of gynecomastia.
Therapy recommendations
- Therapy for gynecomastia consists of therapy for the underlying condition.
- Review of permanent medication due topossible effect on the existing disease; or discontinuation, the substances associated with gynecomastia (then observant waiting).
- Before the age of 15: educate and observe!
- Drug therapy (tamoxifen (antiestrogen); testolactone (aromatase inhibitor)) should be reserved for individual cases with high psychological pressure, as success is very doubtful. Note [EAA Guideline]:
- Selective estrogen receptor modulators (SERMs), aromatase inhibitors, or nonaromatizable androgens are generally not recommended.
- Testosterone treatment should be started only in men with a proven deficit.
- See also under surgical therapy
