The following are the most important diseases or complications that may be contributed to by hantavirus disease:
Respiratory system (J00-J99)
- ARDS (Acute respiratory distress syndrome) – acute respiratory failure in the setting of multiorgan failure.
- Pulmonary edema – accumulation of water in the lungs.
Endocrine, nutritional and metabolic diseases (E00-E90).
Cardiovascular system (I00-I99)
- Cardiovascular failure
- Myocarditis (inflammation of the heart muscle)
- Shock
Liver, gallbladder and bile ducts – Pancreas (pancreas) (K70-K77; K80-K87).
- Hepatitis (inflammation of the liver)
Symptoms and abnormal clinical and laboratory findings not elsewhere classified (R00-R99).
- Microhematuria (presence of blood in the urine (hematuria) detectable by microscopy or test strip (Sangur test )) (long-term sequelae).
- Proteinuria (increased excretion of protein in the urine; no long-term sequelae).
Genitourinary system (kidneys, urinary tract – reproductive organs) (N00-N99).
- Acute renal failure (ANV; see prognostic factors below).
Prognostic factors
Three findings suggest an increased risk of severe acute renal failure (ANV).
| Thrombocytopenia (deficiency of platelets (thrombocytes) in the blood). | 2 points |
| C-reactive protein (CRP; inflammatory parameter) increases to at least 12 times the upper normal range | 1 point |
| Proteinuria (excretion of protein in urine). | 1 point |
Assessment:
- 0 points: Patients are 18% likely to develop severe ANV.
- 1-2 points: Risk increase to 28 or 38%; depending on the patient’s general condition, the risk is too high for outpatient care
- 3-4 points: Patients develop severe ANV with a probability of 50 or 64%.
