The anamnesis (medical history) represents an important component in the diagnosis of fructose intolerance (fructose intolerance). Family history Are there any diseases of the gastrointestinal tract in your family that are common? Are there any hereditary diseases in your family? Social anamnesis Current medical history/systemic medical history (somatic and psychological complaints). Have you noticed symptoms … Fructose Intolerance: Medical History
Nutritional Medicine Nutritional counseling based on nutritional analysis Nutritional recommendations according to a mixed diet taking into account the disease at hand. This means, among other things: Daily total of 5 servings of fresh vegetables and fruits (≥ 400 g; 3 servings of vegetables and 2 servings of fruits). Once or twice a week fresh … Fructose Intolerance: Therapy
Endocrine, nutritional, and metabolic diseases (E00-E90). Food allergy or food intolerance FODMAP intolerance: abbreviation for “fermentable oligo-, di- and monosaccharides and polyols” (engl. “fermentable oligosaccharides (fructans and galactans), disaccharides (lactose) and monosaccharides (fructose) (AND) as well as polyols” (= sugar alcohols, such as maltitol, sorbitol etc. )); FODMAP‘s are, for example, wheat, rye, garlic, onion, … Fructose Intolerance: Or something else? Differential Diagnosis
Fructosuria, intestinal as well as hereditary fructose intolerance therapy Dietary treatment consists of a fructose-free or low-fructose diet, depending on fructose sensitivity. With strict adherence to the diet, symptoms usually improve within a few weeks. It is important to know that by adding glucose to a high-fructose diet, fructose absorption can be largely normalized. The … Fructose Intolerance: Nutritional Therapy
The following are the most important diseases or complications that can be caused by hereditary fructose intolerance: Blood, blood-forming organs – Immune system (D50-D90). Coagulation disorders, unspecified Endocrine, nutritional, and metabolic disorders (E00-E90). De Toni-Fanconi syndrome (synonyms: De Toni-Fanconi complex, glucose-amino acid diabetes) – inherited dysfunction of the energy balance of the proximal tubule cells … Fructose Intolerance: Complications
A comprehensive clinical examination is the basis for selecting further diagnostic steps: General physical examination – including blood pressure, pulse, body temperature, body weight, body height; furthermore: Inspection (viewing). Skin, mucous membranes, and sclerae (white part of the eye) [hypoglycemia (low blood sugar), sweating, tremors, lethargy] Palpation (palpation) of the abdomen (abdomen) (tenderness?, knocking pain?, … Fructose Intolerance: Examination
2nd order laboratory parameters – depending on the results of the medical history, physical examination, etc. Three mutations A149P, A174D and N334K are responsible for circa 95% of all clinical cases in Europe – genetic alteration in aldolase B gene, this is responsible for loss of enzyme function in kidney and liver. Fructose [increased fructose … Fructose Intolerance: Test and Diagnosis
Drug therapy for fructose intolerance is not available.
Optional medical device diagnostics – depending on the results of the medical history, physical examination, laboratory diagnostics, etc. – for differential diagnostic clarification Fructose H2 breath test – on the day of the examination, a baseline value is first obtained from exhaled air. This is followed by the administration of 200 ml of a fructose … Fructose Intolerance: Diagnostic Tests
The following symptoms and complaints may indicate fructose intolerance (fructose intolerance): Leading symptoms (postprandial* /postmeal). Meteorism (flatulence/discharge of winds). Nausea (nausea) Diarrhea (diarrhea) Nonspecific abdominal pain (e.g., cramp-like discomfort). Other possible symptoms or complaints: Hypoglycemia* * (hypoglycemia; in young children). Sweating, tremors, lethargy* * . Cephalgia (headache) Seizures* * [rare] * Due to the rapid … Fructose Intolerance: Symptoms and Complaints
Pathogenesis (development of disease) Fructose intolerances (fructose intolerances) include essential fructosuria, hereditary fructose intolerance, and fructose malabsorption. The first two metabolic disorders are caused by various genetic enzyme defects. Fructose malabsorption (intestinal fructose intolerance) is a disorder in the absorption of fructose via the intestine. In essential fructosuria, a genetic defect leads to a loss … Fructose Intolerance: Causes
