Pancreatic Cance

Pancreatic Cancer: Or something else? Differential Diagnosis

Liver, gallbladder, and bile ducts-pancreas (pancreatic) (K70-K77; K80-K87). Pancreatitis (inflammation of the pancreas). Mouth, esophagus (esophagus), stomach, and intestines (K00-K67; K90-K93). Chronic gastritis (inflammation of the gastric mucosa). Functional dyspepsia (irritable stomach syndrome). Gastroesophageal reflux disease (synonyms: GERD, gastroesophageal reflux disease; gastroesophageal reflux disease (GERD); gastroesophageal reflux disease (reflux disease); gastroesophageal reflux; reflux esophagitis; reflux … Pancreatic Cancer: Or something else? Differential Diagnosis

Pancreatic Cancer: Medical History

Medical history (history of illness) represents a building block in the diagnosis of pancreatic cancer (pancreatic cancer). Family history Does your family have a history of cancer that is common? Social history Is there any evidence of psychosocial stress or strain due to your family situation? Current medical history/systemic history (somatic and psychological complaints). Do … Pancreatic Cancer: Medical History

Pancreatic Cancer: Complications

The following are the most important diseases or complications that may be contributed to by pancreatic cancer (pancreatic cancer): Endocrine, nutritional, and metabolic diseases (E00-E90). Diabetes mellitus Malnutrition [about 80% of all patients]. Circulatory system (I00-I99) Venous thromboembolism* (VTE) – association between the occurrence of VTE and malignancies is referred to as Trousseau syndrome. Musculoskeletal … Pancreatic Cancer: Complications

Pancreatic Cancer: Classification

TNM classification of pancreatic cancer. T Infiltration depth of the tumor T1 <2 cm greatest extent, confined to pancreas (pancreas) only T2 > 2 cm largest extension, limited to pancreas only T3 Spread beyond pancreas T4 Spread to truncus coeliacus or superior mesenteric artery N Lymph node involvement N0 No lymph node metastases N1 Lymph … Pancreatic Cancer: Classification

Pancreatic Cancer: Examination

A comprehensive clinical examination is the basis for selecting further diagnostic steps: General physical examination – including blood pressure, pulse, body weight, height; further: Inspection (viewing). Skin, mucous membranes, and sclerae (white part of the eye) [due tosymptom: painless icterus (jaundice; occlusive icterus?* ), pruritus (itching)] Abdomen (abdomen) Shape of the abdomen? Skin color? Skin … Pancreatic Cancer: Examination

Pancreatic Cancer: Test and Diagnosis

1st-order laboratory parameters-obligatory laboratory tests. Small blood count Differential blood count Inflammatory parameter – CRP (C-reactive protein) Pancreatic parameters – amylase, lipase, trypsin and elastase [increase in serum lipase value = early alarm]. Laboratory parameters 2nd order – depending on the results of the history, physical examination, etc. – for differential diagnostic clarification (and treatment … Pancreatic Cancer: Test and Diagnosis

Pancreatic Cancer: Drug Therapy

Therapeutic targets Improvement of the symptomatology Reduction of tumor mass Palliative (palliative treatment) Therapy recommendations The most important therapeutic procedure is surgery (see “Surgical therapy” below). In pancreatic cancer, chemotherapy may be necessary in addition to surgical therapy, depending on the stage of the disease. A distinction can be made between neoadjuvant chemotherapy (i.e., chemotherapy … Pancreatic Cancer: Drug Therapy

Pancreatic Cancer: Diagnostic Tests

Mandatory medical device diagnostics. Abdominal ultrasonography (ultrasound examination of abdominal organs; in this case: Pancreatic sonography/ultrasound examination of the pancreas) – for basic diagnosis [most common malignant (malignant) tumor of the pancreas: ductal adenocarcinoma; this shows up sonographically echo-poor, irregular and polycyclic limited; due topancreatic cyst see below]. Endosonography (endoscopic ultrasound (EUS); ultrasound examination performed … Pancreatic Cancer: Diagnostic Tests

Pancreatic Cancer: Surgical Therapy

Localized, or non-metastatic, pancreatic cancer is divided into: Primarily resectable tumor → in this case, RO resection (removal of the tumor in healthy tissue; no tumor tissue is detectable in the resection margin on histopathology) and cure are possible Borderline or borderline resectable tumor (here: infiltration of the portal vein and/or superior mesenteric vein). Locally … Pancreatic Cancer: Surgical Therapy

Pancreatic Cancer: Prevention

To prevent pancreatic cancer (pancreatic cancer), attention must be paid to reducing individual risk factors. Behavioral risk factors Diet High consumption of red meat, i.e., muscle meat of pork, beef, lamb, veal, mutton, horse, sheep, goat; this is classified by the World Health Organization (WHO) as “probably carcinogenic to humans,” i.e., carcinogenicMeat and sausage products … Pancreatic Cancer: Prevention

Pancreatic Cancer: Symptoms, Complaints, Signs

In most cases, there are no early symptoms. Initial warning signs may include: Painless icterus (jaundice) (periampullary carcinoma: pancreatic tumors in the head not infrequently compress the ampulla hepatopancreatica). New onset type 2 diabetes Annular back pain without orthopedic cause The combination of a palpable, painlessly enlarged bulging elastic gallbladder under the right costal arch … Pancreatic Cancer: Symptoms, Complaints, Signs

Pancreatic Cancer: Causes and Signs

Pathogenesis (disease development) More than 95% of pancreatic cancers are ductal adenocarcinoma. This arises from malignant degeneration of exocrine pancreatic tissue (production of digestive enzymes). The pathogenesis is not yet fully understood. It is assumed that, as in the case of other malignant neoplasms comparable to colorectal carcinoma, mutations (changes in genetic material) gradually lead … Pancreatic Cancer: Causes and Signs