Bowen's Disease

Bowen’s Disease: Diagnostic Tests

Optional medical device diagnostics – depending on the results of the history, physical examination, laboratory diagnostics, and obligatory medical device diagnostics – for differential diagnostic clarification. Dermoscopy (reflected-light microscopy; increases diagnostic certainty) [pigmented or nonpigmented; vessels: regular pattern, glomerular vessels; scaling often present; typical: linear and radial arrangement of brown or gray dots; rarely clods … Bowen’s Disease: Diagnostic Tests

Bowen’s Disease: Surgical Therapy

In Bowen’s disease, the affected area of skin in healthy tissue must be excised (cut out). Fulguration and laser evaporation (laser beam vaporization) are possible in the anal canal.

Bowen’s Disease: Prevention

To prevent Bowen disease, attention must be paid to reducing individual risk factors. Behavioral risk factors UV light exposure (sun; solarium). Environmental pollution – intoxications (poisonings). Arsenic Sun exposure Note: Bowen’s disease also occurs in non-light-exposed areas such as the lower legs. There it is manifested by scaly reddish plaques (areal or plate-like substance proliferation … Bowen’s Disease: Prevention

Bowen’s Disease: Symptoms, Complaints, Signs

The following symptoms and complaints may indicate Bowen disease or erythroplasia quéyrat: Bowen disease Leading symptoms Flat, sharply demarcated skin lesions; limited, easily vulnerable. Slowly growing, red plaque (areal or plate-like substance proliferation of the skin), which is partly keratotic (scaly) or erosively crusted; rarely also smooth, red or red-brown surface Localization Light-exposed areas (face, … Bowen’s Disease: Symptoms, Complaints, Signs

Bowen’s Disease: Causes

Pathogenesis (disease development) Bowen disease is an intraepidermal carcinoma in situ (literally, “cancer in situ”) of the skin. Histologically, atypical dyskeratotic cells are seen. Queyrat’s erythroplasia is considered Bowen’s disease of the transitional mucosa. It is also a carcinoma in situ. In the pathogenesis, infection with HPV type 16 is of great importance. Etiology (Causes) … Bowen’s Disease: Causes

Bowen’s Disease: Therapy

General measures Nicotine restriction (refraining from tobacco use). Limited alcohol consumption (men: max. 25 g alcohol per day; women: max. 12 g alcohol per day). Aim for normal weight! Determination of BMI (body mass index, body mass index) or body composition by means of electrical impedance analysis and, if necessary, participation in a medically supervised … Bowen’s Disease: Therapy

Bowen’s Disease: Medical History

Medical history (history of illness) represents an important component in the diagnosis of Bowen disease. Family history Social history Current anamnesis/systemic anamnesis (somatic and psychological complaints). What skin or mucosal changes have you noticed? How long have these changes existed? Where are the changes located? Is only one or several body parts affected? Vegetative anamnesis … Bowen’s Disease: Medical History

Bowen’s Disease: Or something else? Differential Diagnosis

Skin and subcutaneous (L00-L99). Contact dermatitis Lichen ruber (nodular lichen) Nummular eczema (synonyms: bacterial eczematoid, dermatitis nummularis, dysregulatory microbial eczema, microbial eczema) – unclear disease resulting in eczema characterized by sharply demarcated, coin-shaped, itchy foci of disease, some of which are weeping and crusty. They occur mainly on the extensor sides of the extremities. Psoriasis … Bowen’s Disease: Or something else? Differential Diagnosis

Bowen’s Disease: Complications

The following are the most important diseases or complications that may be contributed to by Bowen’s disease or erythroplasia Queyrat: Neoplasms – Tumor diseases (C00-D48). Bowen carcinoma (Bowen skin cancer; spinocellular carcinoma with histologically bowenoid cell polymorphism). Spinocellular carcinoma of the penis (squamous cell carcinoma; progression of erythroplasia queyrate into invasive spinocellular carcinoma is; approximately … Bowen’s Disease: Complications

Bowen’s Disease: Examination

A comprehensive clinical examination is the basis for selecting further diagnostic steps: General physical examination – including blood pressure, pulse, body weight, height; further: Inspection (viewing) of the skin and mucous membranes [Bowen’s disease: flat, sharply demarcated skin lesions; limited, easily injured; sometimes keratotic (scaly) skin lesions. Bowen’s disease can generally occur all over the … Bowen’s Disease: Examination

Bowen’s Disease: Test and Diagnosis

1st order laboratory parameters – obligatory laboratory tests. Histopathologic examination (fine tissue examination) from the excised area (collection area).

Bowen’s Disease: Drug Therapy

Therapeutic target Cure Therapy recommendations First-line therapy: excision (surgical removal of the tissue) in healthy tissue. If necessary, local (“local”) therapy with 5-fluorouracil (5-FU), Imiquimod. See also under “Further therapy“.