What are reticulocytes? Reticulocytes are immature red blood cells (so-called erythrocytes). They no longer have a cell nucleus, but they are still able to carry out metabolic processes, as some cell organelles are still functional. One of these cell organelles is the endoplasmic reticulum. In addition, the genetic information (RNA) is stored in the reticulocytes. … The Reticulocytes
In which diseases are reticulocytes elevated? The classic disease associated with an increased reticulocyte count is anemia. Anemia describes an anaemia. It is characterized by a decreased red blood cell count, i.e. a reduced number of red blood cells, or by a decreased concentration of red blood pigment (so-called hemoglobin). The body tries to compensate … In which diseases are reticulocytes elevated? | The Reticulocytes
What is a reticulocyte crisis? A reticulocyte crisis describes a strong increase of reticulocytes in the blood. This is due to increased blood formation. The crisis can occur after a heavy bleeding, as the body tries to replace the lost blood cells. In addition, it can occur during a substitution therapy with iron, folic acid … What is a reticulocyte crisis? | The Reticulocytes
Structure Hemoglobin is a protein in the human body that has important functions for the transport of oxygen in the blood. Proteins in the human body are always made up of multiple amino acids linked together. The amino acids are partly taken up by the body with food, partly the body can also convert other … Hemoglobin
Hemoglobin too low Since every red blood cell has the hemoglobin molecule, the hemoglobin value is a meaningful marker for the amount of red blood cells in the bloodstream. During a blood test, the Hb value can be determined in medical laboratories and the quantity of red blood cells can be estimated on the basis … Hemoglobin too low | Hemoglobin
Haemoglobinopathy Hemoglobinopathy is the umbrella term for diseases that cause changes in hemoglobin. These are genetically predisposed. The best known are sickle cell anemia and thalassemia (divided into alpha and beta thalassemia). These diseases are either caused by a mutation, i.e. a change in the proteins (sickle cell anaemia) or by a reduced production of … Haemoglobinopathy | Hemoglobin
Standard values The standard values for hemoglobin concentration differ from child to adult, but also between men and women. Reference ranges are 12.9-16.2 g/dl for adult males, 12-16 g/dl for females and 19 g/dl for neonates. In this range are 96% of all values of healthy persons. However, when symptoms of anemia become noticeable varies … Standard values | Hemoglobin
The haematocrit is a blood value that exclusively reflects the cellular components (more precisely the number of erythrocytes) of the blood. In general, blood consists of a liquid component, the blood plasma and many different cells. As mentioned above, these cells are summarized as hematocrit (abbreviation Hkt), whereby the value actually only refers to the … Hematocrit
Normal hematocrit value Normally, a hematocrit value should be between 37-45% for women and slightly higher for men, namely between 42-50%. It should be noted, however, that these normal values may also vary slightly. There are patients who are completely healthy although their hematocrit value does not quite correspond to the normal range. On the … Normal hematocrit value | Hematocrit
Low hematocrit A haematocrit that is too low is when the value is less than 37% in women and 42% in men. This may be due to the patient having drunk too much or having received a fluid replacement (e.g. a NaCl solution) for a long time. Since an increased blood volume is then produced … Low hematocrit | Hematocrit
Meaning of the abbreviations MCH = mean corpuscular haemoglobin MCV = mean cell volume MCHC = mean corpuscular haemoglobin concentration RDW = red cell distribution width All these abbreviated parameters are used to describe the red blood count, i.e. the red blood cells (erythrocytes) in more detail. They are particularly important in the case of … Erythrocyte Parameters
MCH MCH describes the average amount of hemoglobin that a red blood cell contains. It is calculated from hemoglobin count of red blood cells. The normal range is 28-34 pg. An increase or decrease in MCH is usually accompanied by a change in MCV in the same direction. An increase above the norm indicates macrocytic … MCH | Erythrocyte Parameters
