Products In many countries, no finished medicinal products containing alfatradiol are commercially available. In Germany, preparations for external use are available (e.g., Ell-Cranell). Structure and properties Alfatradiol (C18H24O2, Mr = 272.4 g/mol) or 17α-estradiol is a stereoisomer of the female sex hormone 17β-estradiol. Effects Alfatradiol inhibits the enzyme 5α-reductase, thereby inhibiting the synthesis of the … Alfatradiol
Products Finasteride is commercially available as film-coated tablets (prostate: Proscar, generic, 5 mg; hair loss: Propecia, generic, 1 mg). It has been approved in many countries since 1993. Propecia was launched five years later, in 1998. Structure and properties Finasteride (C23H36N2O2, Mr = 372.5 g/mol) is a 4-azasteroid and structurally related to testosterone. It exists … Finasteride
Products Dutasteride is commercially available in capsule form (Avodart). It is also available in combination with the alpha blocker tamsulosin (Duodart); see dutasteride tamsulosin. The active ingredient has been approved in many countries since 2003. Generics were registered in 2017. Generic versions of Duodart were approved in 2018. Structure and properties Dutasteride (C27H30F6N2O2, Mr = … Dutasteride
Products The 5alpha-reductase inhibitor dutasteride and the alpha-blocker tamsulosin are commercially available as a fixed combination in the form of capsules (Duodart, generics). The drug has been approved in many countries since 2010. Structure and properties Dutasteride (C27H30F6N2O2, Mr = 528.5 g/mol) is a 4-azasteroid and structurally closely related to finasteride. It exists as a … Dutasteride, Tamsulosin
