Carboanhydrase Inhibitors

Brinzolamide

Products Brinzolamide is form of eye drops commercially available (Azopt) and approved in many countries since 1991. Generic versions were released in 2015. Brinzolamide has also been available in a fixed combination with timolol since 2009 (Azarga). In 2015, a fixed combination with brimonidine was approved; see brinzolamide brimonidine (Simbrinza). Structure and properties Brinzolamide (C12H21N3O5S3, … Brinzolamide

Dorzolamide

Products Dorzolamide is commercially available in the form of eye drops (Trusopt). Fixed combinations with timolol (Cosopt) and generics are also available. Dorzolamide has been approved in many countries since 1995. Structure and properties Dorzolamide (C10H16N2O4S3, Mr = 324.4 g/mol) is a sulfonamide. It is present in drugs as dorzolamide hydrochloride, a white crystalline powder … Dorzolamide