Caspofungin

Products Caspofungin must be administered as an infusion solution because of its low oral bioavailability (Cancidas, generics). It has been approved in many countries since 2002 and was the first member of the echinocandins. Structure and properties Caspofungin is present in drugs as caspofungin diacetate (C52H88N10O15 – 2C2H4O2, Mr = 1213.42 g/mol), a hygroscopic white … Caspofungin

Anidulafungin

Products Anidulafungin is commercially available as a powder for the preparation of an infusion solution (Ecalta, generics). It has been approved in many countries since 2009. Structure and properties Anidulafungin (C58H73N7O17, Mr = 1140.3 g/mol) is a cyclic lipopeptide. It is a semisynthetic echinocandin obtained from a fermentation product of . It exists as a … Anidulafungin

Micafungin

Products Micafungin is commercially available as a powder for the preparation of an infusion solution (Mycamine). It was approved in many countries in 2012. Structure and properties Micafungin (C56H70N9NaO23S, Mr = 1292.3 g/mol) is a complex molecule obtained as a derivative of a fermentation product of the fungus F-11899. It is present in the drug … Micafungin