Codeine: Effects, Usage, Side Effects

How codeine works Codeine dampens the cough reflex by inhibiting the cough center in the brain stem. According to current doctrine, this codeine effect is mainly due to morphine – a metabolic intermediate (metabolite) to which codeine is converted in small amounts in the liver. However, there is also evidence that codeine-6-glucuronide is responsible for … Codeine: Effects, Usage, Side Effects