Folic Acid Antagonists

Dapsone

Products Dapsone is approved in Germany in tablet form (Dapsone-Fatol). In the USA, it is additionally on the market as a gel for the treatment of acne (Aczone). No preparations are currently registered in many countries. Structure and properties Dapsone or 4,4′-diaminodiphenylsulfone (C12H12N2O2S, Mr = 248.3 g/mol) is a sulfone and aniline derivative with structural … Dapsone

Pralatrexate

Products Pralatrexate is commercially available as an infusion solution (Folotyn). It has been approved in many countries since 2013. Structure and properties Pralatrexate (C23H23N7O5, Mr = 477.5 g/mol) is a folic acid analog and exists as a racemate. It is a white to yellow substance that is soluble in water. Effects Pralatrexate (ATC L01BA05) has … Pralatrexate