Products Lenalidomide is commercially available in the form of hard capsules (Revlimid). It has been approved in many countries since 2007. Generic versions were registered in 2019. Structure and properties Lenalidomide (C13H13N3O3, Mr = 259.3 g/mol) is a derivative of thalidomide and exists as a racemate. Effects Lenalidomide (ATC L04AX04) has immunomodulatory and antiangiogenic properties. … Lenalidomide
Products Glatiramer acetate is commercially available as a solution for injection (Copaxone). It has been approved in many countries since 2004. Generic products were registered in 2015. Structure and properties Glatiramer acetate is the acetate salt of a synthetic polypeptide of the four natural amino acids glutamic acid, alanine, tyrosine, and lysine. The average molecular … Glatiramer Acetate
Products Teriflunomide is commercially available in the form of film-coated tablets (Aubagio). It was approved in many countries in 2013. Teriflunomide can be taken perorally, unlike earlier MS medications, and does not need to be injected. Structure and properties Teriflunomide (C12H9F3N2O2, Mr = 270.2 g/mol) is the active metabolite of the prodrug leflunomide (Arava), which … Teriflunomide
Products Leflunomide is commercially available in the form of film-coated tablets (Arava, generics). It has been approved in many countries since 1998. In 2011, generic versions went on sale in many countries. Structure and properties Leflunomide (C12H9F3N2O2, Mr = 270.2 g/mol) is an isoxazole carboxamide. It is a prodrug and is biotransformed in the intestine … Leflunomide
Products Imiquimod is commercially available as a cream in single-use sachets (Aldara 5%). It has been approved in many countries since 1999. Since 2014, a preparation containing 3.75% imiquimod has also been registered in many countries (Zyclara). Structure and properties Imiquimod (C14H16N4, Mr = 240.3 g/mol) is an imidazoquinoline amine structurally similar to nucleoside analogs … Imiquimod: Drug Effects, Side Effects, Dosage and Uses
Products Pomalidomide is commercially available in the form of hard capsules (Imnovid). It has been approved in many countries since 2014. It has been registered in the EU and the United States since 2013. Structure and properties Pomalidomide (C13H11N3O4, Mr = 273.2 g/mol) is an amino derivative of thalidomide and a racemate. It is also … Pomalidomide
