Products Gemfibrozil is commercially available in the form of film-coated tablets (Gevilon, Gevilon Uno). It has been approved in many countries since 1985. Structure and properties Gemfibrozil (C15H22O3, Mr = 250.3 g/mol) exists as a white powder that is practically insoluble in water. Effects Gemfibrozil (ATC C10AB04) has lipid-lowering properties. It lowers VLDL, triglycerides, total … Gemfibrozil
Products Fenofibric acid was approved in many countries in 2013 in sustained-release capsule form (Trilipix). The capsules are not commercially available. Structure and properties Fenofibric acid (C17H15ClO4, Mr = 318.8 g/mol) is present in the drug as the choline salt (choline fenofibrate), a white to yellow powder that is very soluble in water. Fenofibric acid … Fenofibric Acid
Products Fenofibrate is commercially available in the form of capsules (lipanthyl). It has been approved in many countries since 1977. In 2014, a fixed combination with simvastatin was registered (Cholib); see Fenofibrate Simvastatin. Structure and properties Fenofibrate (C20H21ClO4, Mr = 360.8 g/mol) exists as a white crystalline powder that is practically insoluble in water. It … Fenofibrate
Products Ciprofibrate was commercially available in many countries in capsule form (Hyperlipen, off label). It was approved in 1993 and has not been available since 2013. Structure and properties Ciprofibrate (C13H14Cl2O3, Mr = 289.2 g/mol) is a racemate and a phenoxyisobutyric acid derivative. It exists as a white to pale yellow powder that is practically … Ciprofibrate
Products Etofibrate is commercially available in the form of sustained-release capsules (Lipo-Merz retard). The drug is no longer registered in many countries. Structure and properties Etofibrate (C18H18ClNO5, Mr = 363.8 g/mol is a diester of clofibric acid and nicotinic acid linked via ethylene glycol. Effects Etofibrate (ATC C10AB09) is lipid-lowering. It lowers elevated cholesterol and … Etofibrate
Products Bezafibrate is commercially available in the form of sustained-release tablets (Cedur retard). It has been approved in many countries since 1979. Structure and properties Bezafibrate (C19H20ClNO4, Mr = 361.8 g/mol) lies as a white crystalline powder that is practically insoluble in water. Effects Bezafibrate (ATC C10AB02) primarily lowers elevated blood triglyceride levels. It has … Bezafibrate
