Melatonin Receptor Agonists

Tasimelteon

Products Tasimelteon was approved in the United States in 2014 and in the EU in 2015 in capsule form (Hetlioz). The drug is not currently registered in many countries. Structure and properties Tasimelteon (C15H19NO2, Mr = 245.3 g/mol) exists as a white crystalline powder that is sparingly soluble in water. It is structurally related to … Tasimelteon

Ramelteon

Products Ramelteon has been approved in the United States since 2005 in the form of film-coated tablets (Rozerem). The drug is not currently registered in many countries. The EMA had rejected approval in the EU because it judged the evidence of efficacy to be insufficient. Structure and properties Ramelteon (C16H21NO2, Mr = 259.3 g/mol) exists … Ramelteon