Products Fesoterodine is commercially available in the form of sustained-release tablets (Toviaz). It has been approved in the EU since 2007 and in many countries since 2008. Structure and properties Fesoterodine (C26H37NO3, Mr = 411.58 g/mol) is present in drugs as fesoterodine fumarate. It is an ester prodrug and is rapidly and completely hydrolyzed to … Fesoterodine
Products Aclidinium bromide is commercially available as a powder inhalation (Bretaris Genuair, Eklira Genuair). It is administered with the Genuair inhaler and was approved in the EU and US in 2012. In many countries, it entered the market in 2013. In the EU, a fixed-dose combination with formoterol was released in 2014 (Brimica Genuair). Structure … Aclidinium Bromide
Products Tolterodine is commercially available in the form of sustained-release capsules (Detrusitol SR). It has been approved in many countries since 2000. Its successor product, fesoterodine (Toviaz), was launched in 2008 and desfesoterodine (Tovedeso) in 2019. A non-retarded preparation is also commercially available in the United States (Detrol). Structure and properties Tolterodine (C22H31NO, Mr = … Tolterodine
Products Tropicamide is commercially available in the form of eye drops, as an ophthalmic insert, and as a solution for injection. This article refers to the eye drops. The active ingredient has been approved in many countries since 1957. Structure and properties Tropicamide (C17H20N2O2, Mr = 284.4 g/mol) exists as a white crystalline powder that … Tropicamide
Products Trospium chloride is commercially available in the form of dragées (Spasmo-Urgenin Neo, Spasmex). It has been approved in many countries since 1983. Structure and properties Trospium chloride (C25H30ClNO3, Mr = 428.0 g/mol) is a quaternary amine that exists as a chloride salt. It is a fine, colorless to slightly yellow, crystalline substance. Trospium chloride … Trospium Chloride
Products Atropine is commercially available in the form of eye drops, drops, and as a solution for injection. It has been approved in many countries since 1987. Medicinal plants containing atropine have been used medicinally for much longer. Structure and properties Atropine (C17H23NO3, Mr = 289.4 g/mol) is a tertiary amine and belongs to the … Atropine
Products Clidinium bromide is commercially available in the form of dragées in combination with chlordiazepoxide (Librax). It has been approved in many countries since 1961. Structure and properties Clidinium bromide (C22H26BrNO3, Mr = 432.4 g/mol) Effects Clidinium bromide (ATC A03CA02) has anticholinergic and spasmolytic properties on smooth muscle. Indications In combination with chlordiazepoxide: Gastrointestinal or … Clidinium Bromide
Products Desfesoterodine was approved in many countries in 2019 in sustained-release tablet form (generic, tovedeso). Structure and properties Desfesoterodine (C22H31NO2, Mr = 341.5 g/mol) is the active metabolite of the prodrug fesoterodine as well as tolterodine (detrusitol). It is also referred to as 5-hydroxymethyltolterodine. In the drug, it is present as desfesoterodine succinate. Effects Desfesoterodine … Desfesoterodine
Products Oxybutynin is commercially available in tablet form and as a transdermal patch (Ditropan, Kentera). It has been approved in many countries since 1988, and the transdermal patch has been available since 2007. Extemporaneous formulations are also produced; see Intravesical oxybutynin solution (for use in the urinary bladder). Other dosage forms have been released in … Oxybutynin
