Products Crisaborole was approved in the United States in 2016 as an ointment (Eucrisa, 2%). Crisaborole is not currently registered in many countries. Structure and properties Crisaborole (C14H10BNO3, Mr = 251.0 g/mol) is a low molecular weight boron compound with a nonsteroidal structure. It belongs to the phenoxybenzoxaboroles. Due to its small size, the compound … Crisaborol
Products Apremilast is commercially available in the form of film-coated tablets (Otezla). It was approved in the United States in 2014 and in many countries and the EU in 2015. Structure and properties Apremilast (C22H24N2O7S, Mr = 460.5 g/mol) is a dioxoisoindole acetamide derivative. Effects Apremilast (ATC L04AA32) has immunomodulatory and anti-inflammatory properties. The effects … Apremilast
Products Roflumilast is commercially available in the form of film-coated tablets (Daxas). The drug was approved in many countries in 2011. Structure and properties Roflumilast (C17H14Cl2F2N2O3, Mr = 403.2 g/mol) has a nonsteroidal benzamide structure and is unrelated to the glucocorticoids. It exists as a white powder that is practically insoluble in water. Effects Roflumilast … Roflumilast
