Products Treprostinil is commercially available as an infusion solution (Remodulin, generic). It has been approved in many countries since 2004. Structure and properties Treprostinil (C23H34O5, Mr = 390.5 g/mol) is a synthetic prostacyclin. Effects Treprostinil (ATC B01AC21) has vasodilator and antiplatelet properties. Indications Primary pulmonary hypertension Pulmonary arterial hypertension
Products Epoprostenol is commercially available as a lyophilizate (Flolan, Veletri). It has been approved in many countries since 2000. Structure and properties Epoprostenol (C20H32O5, Mr = 352.5 g/mol) is a synthetic prostacyclin. Effects Epoprostenol (ATC B01AC09) has antiplatelet and vasodilatory properties. Indications Pulmonary hypertension
Products Iloprost is commercially available as an infusion solution concentrate and as a solution for nebulizers (Ilomedin, Ventavis). It has been approved in many countries since 2005. Structure and properties Iloprost (C22H32O4, Mr = 360.5 g/mol) is an analog of prostacyclin. It is present in drugs as iloprosttrometamol, an oily substance that is sparingly soluble … Iloprost