Molybdenum is known to be a cofactor for three enzymes: Xanthine oxidase supports the hydroxylation reaction of nucleotides – precursors of DNA (genetic information) and RNA (transmits genetic information for protein formation) – and uric acid formation – uric acid is a highly potent water-soluble antioxidant. Xanthine dehyde oxidase plays an important role in the … Molybdenum: Functions
Interactions of molybdenum with other micronutrients (vital substances): Copper In ruminants, it has been demonstrated that increased intake of molybdenum can lead to copper deficiency. Preparations containing both sulfur and molybdenum, also known as thiomolybdenum, can prevent absorption of copper. This interaction between thiomolybdenums and copper does not apply to humans. An older study reported … Molybdenum: Interactions
Recommendation of the German Nutrition Society (DGE) [µg/day]. Infants (0 to less than 4 months) 7 Children (7 to under 10 years) 40-80 Infants (4 to under 12 months) 20-40 Children (10 to under 15 years) 50-100 Children (1 to under 4 years) 25-50 Teenagers and adults (15 years and older) 50-100 Children (4 to … Molybdenum: Food
Molybdenum deficiency has never been observed in healthy individuals. The only documented case of molybdenum deficiency was in a patient with Crohn’s disease who had received long-term intravenous nutrition without molybdenum supplementation. He developed tachycardia (rapid heartbeat), rapid shallow breathing, headache, became night blind, and eventually went into a coma. Furthermore, his blood showed low … Molybdenum: Symptoms of Deficiency
The European food safety authority (EFSA) last evaluated vitamins and minerals for safety in 2006 and set a so-called Tolerable Upper Intake Level (UL) for each micronutrient, provided sufficient data were available. This UL reflects the maximum safe level of a micronutrient that will not cause adverse effects when taken daily from all sources for … Molybdenum: Safety Assessment
Molybdenum was not included in the National Consumption Survey II (2008). Regarding the intake of molybdenum in the German population, data exist only from a study by Holzinger et al. in 1998. Regarding the supply situation, it can be stated: On average, men take 100 µg and women 89 µg molybdenum per day to themselves … Molybdenum: Supply Situation
The intake recommendations (D-A-CH reference values) of the German Nutrition Society (DGE) presented below are aimed at healthy people of normal weight. They do not refer to the supply of sick and convalescent people. Individual requirements may therefore be higher than the DGE recommendations (e.g. due to diet, consumption of stimulants, long-term medication, etc.). Furthermore, … Molybdenum: Supply
