Medical history (history of illness) represents an important component in the diagnosis of myalgia (muscle pain). Family history Is there a family history of muscle or neurologic disorders? Social history Current medical history/systemic history (somatic and psychological complaints). How long has the pain been present? Has the pain changed? Become stronger? Where exactly is the … Muscle Pain (Myalgia): Medical History
Blood, blood-forming organs – immune system (D50-D90). Sarcoidosis (synonyms: Boeck’s disease; Schaumann-Besnier’s disease) – systemic disease of connective tissue with granuloma formation (skin, lungs, and lymph nodes). Endocrine, nutritional and metabolic diseases (E00-E90). Carnitine palmitoyl transferase deficiency (CPT1, CPT2) – most common autosomal recessive inherited disorder of lipid metabolism affecting skeletal muscle; most common cause … Muscle Pain (Myalgia): Or something else? Differential Diagnosis
A comprehensive clinical examination is the basis for selecting further diagnostic steps: General physical examination – including blood pressure, pulse, body temperature, body weight, body height; further: Inspection (viewing) of the skin and mucous membranes. Auscultation (listening) of the heart Auscultation of the lungs Palpation (palpation) of the abdomen (abdomen), etc. Neurological examination [due todifferential … Muscle Pain (Myalgia): Examination
Therapy target Complaint relief or elimination of symptoms. Therapy recommendations If necessary, analgesia until definitive therapy when the diagnosis is confirmed. Statin-associated muscle pain (SAMS) [guidelines: S1 guideline]: statin therapy (HMG-CoA reductase inhibitor) can be continued in a controlled manner at the same or reduced dose if Tolerable or no muscle symptoms are present, and … Muscle Pain (Myalgia): Drug Therapy
Optional medical device diagnostics – depending on the results of the history, physical examination, and obligatory laboratory parameters – for differential diagnostic clarification. Electromyography (EMG; measurement of electrical muscle activity) – if there is evidence of myotonic disease (inflammatory or degenerative myopathy or even neurogenic damage). X-rays of spine, ribs or other joints/bones – if … Muscle Pain (Myalgia): Diagnostic Tests
The following symptoms and complaints may indicate myalgia (muscle pain): Stabbing/burning/tearing (pain character). Muscle soreness Cramp-like Occurrence after stress Muscle pain may be local (localized) or diffuse (generalized). The pain may occur as continuous pain or intermittently. In most myopathies (muscle diseases), the pain often occurs intermittently, although it is a chronic disease! Warning signs … Muscle Pain (Myalgia): Symptoms, Complaints, Signs
Therapy for myalgia (muscle pain) depends on the cause. General measures Physical activity respectively sports activity (see below). Aim for normal weight!Determination of BMI (body mass index, body mass index) or body composition by means of electrical impedance analysis and, if necessary, participation in a medically supervised weight loss program or program for underweight. For … Muscle Pain (Myalgia): Therapy
1st order laboratory parameters – obligatory laboratory tests. Small blood count Differential blood count Inflammatory parameters – CRP (C-reactive protein) or ESR (erythrocyte sedimentation rate). Creatine kinase (CK) (isoenzyme CK-MM) – the most important parameter in the detection of muscle diseases (polymyositis, dermatomyositis, but also in infectious myositis) Attention! Even in healthy individuals after heavy … Muscle Pain (Myalgia): Test and Diagnosis
