The following histological types of Hodgkin’s disease are distinguished:
- Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) 5 %.
- Classical Hodgkin lymphoma with
- Nodular sclerosing type (NSHL) (circa 60%).
- Mixed type (MCHL) (circa 30 %)
- Lymphocyte-rich type (circa 4 %)
- Lymphocyte-poor type (< 1%)
Based on the findings of clinical staging, but independent of histologic type, Hodgkin lymphoma is classified into the following four stages according to the Ann Arbor classification:
Stage | Features |
I | Involvement of a lymph node region or involvement of an extralymphatic (“outside the lymph nodes”) organ/district |
II | Involvement of ≥ 2 lymph node regions or localized involvement of an extralymphoid organ/district and its lymph nodes on one side of the diaphragm |
III | Involvement of ≥ 2 lymph node regions or extralymphoid organs/districts on either side of diaphragm |
IV | Disseminated (“spreading”) organ infestation |
A | No defined general symptoms |
B |
Defined general symptoms (B symptoms).
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Based on the above, patients are divided into risk groups:
Risk groups | Stages according to the Ann Arbor classification |
Early stages |
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Middle stages(intermediate stage) |
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Advanced stages |
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According to this classification, therapy is carried out according to the stage.