Integrase Inhibitors

Effects

Integrase inhibitors have antiviral against HIV viruses. They inhibit the catalytic activity of HIV integrase, which is an HIV-encoded enzyme required for viral replication. Integrase inhibition prevents integration of the HIV genome into the host cell genome during the early phase of infection.

Indications

For the treatment of infection with the HIV virus (HIV).

Active ingredients

  • Bictegravir (Biktarvy)
  • Dolutegravir (Tivicay)
  • Elvitegravir (Stribild)
  • Raltegravir (Isentress)